Molecular basis for differential modulation of BK channel voltage-dependent gating by auxiliary γ subunits
Rockefeller University Press -- The Journal of General Physiology
DOI 10.1085/jgp.201511356

The marked difference in the efficacy of BKγ subunits in shifting the voltage dependence of BK activation depends mainly on the TM segment and a neighboring intracellular cluster of positively charged amino acids.