Et3B-mediated and palladium-catalyzed direct allylation of β-dicarbonyl compounds with Morita–Baylis–Hillman alcohols
Beilstein Institut -- Beilstein Journal of Organic Chemistry
DOI 10.3762/bjoc.12.234
Keyword(s)
  1. allylic substitution
  2. Morita–Baylis–Hillman
  3. palladium
  4. triethylborane
Abstract(s)

A practical and efficient palladium-catalyzed direct allylation of β-dicarbonyl compounds with both cyclic and acyclic Morita–Baylis–Hillman (MBH) alcohols, using Et3B as a Lewis acid promoter, is described herein. A wide range of the corresponding functionalized allylated derivatives have been obtained in good yields and with high selectivity.