Zika virus non-structural protein NS4A restricts eye growth in Drosophila through regulation of JAK/STAT signaling
The Company of Biologists Ltd -- Disease Models & Mechanisms
DOI 10.1242/dmm.040816
Keyword(s)
  1. Drosophila
  2. Eye development
  3. JAK/STAT signaling
  4. Host-pathogen interaction
  5. Zika virus
Abstract(s)
Abstract

Summary: Our study provides evidence that Zika virus infection in Drosophila results in restricted growth of the developing eye and wing through regulation of JAK/STAT and Notch signaling, respectively.