Is widowhood a specific risk factor associated with more rapid cognitive decline among cognitively unimpaired older adults with higher levels of brain β-amyloid, the Alzheimer disease biomarker?
In this cohort study of 257 community-dwelling cognitively unimpaired older adults, widowhood and β-amyloid were additively and interactively associated with cognitive decline. These results were independent of demographic factors, cardiovascular disease risk, depression, health-related behaviors, and social support factors.
These findings suggest that widowhood may be an understudied risk factor for cognitive decline associated with Alzheimer disease and highlight the need for increased research and clinical attention to this high-risk group.
https://www.researchpad.co/tools/openurl?pubtype=article&doi=10.1001/jamanetworkopen.2020.0121&title=Associations of Widowhood and Î²-Amyloid With Cognitive Decline in Cognitively Unimpaired Older Adults&author=&keyword=&subject=Research,Original Investigation,Online Only,Geriatrics,
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