Nanoscale Research Letters
Springer US
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Water-Soluble Fullerenol with Hydroxyl Group Dependence for Efficient Two-Photon Excited Photodynamic Inactivation of Infectious Microbes
Volume: 15
DOI 10.1186/s11671-020-03329-6
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Abstract

We successfully prepared water-soluble fullerenol [C60(OH)46] that exhibited a high singlet oxygen quantum yield and efficiently generated reactive oxygen species. Additionally, the water-soluble C60(OH)46 with a higher composition of exposed hydroxyl groups had superior two-photon stability and characteristics compared with that with a lower composition of such groups. Therefore, the prepared fullerenol can be an effective two-photon photosensitizer. The water-soluble C60(OH)46 had favorable two-photon properties. During two-photon photodynamic therapy, the water-soluble C60(OH)46 had substantial antimicrobial activity against Escherichia coli at an ultralow-energy level of 211.2 nJ pixel−1 with 800 scans and a photoexcited wavelength of 760 nm.

Keywords
https://www.researchpad.co/tools/openurl?pubtype=article&doi=10.1186/s11671-020-03329-6&title=Water-Soluble Fullerenol with Hydroxyl Group Dependence for Efficient Two-Photon Excited Photodynamic Inactivation of Infectious Microbes&author=Wen-Shuo Kuo,Jiu-Yao Wang,Chia-Yuan Chang,Jui-Chang Liu,Yu-Ting Shao,Yen-Sung Lin,Edmund Cheung So,Ping-Ching Wu,&keyword=Water-soluble fullerenol,Composition of exposed hydroxyl groups,Singlet oxygen quantum yield,Reactive oxygen species,Two-photon excitation,&subject=Nano Express,