PLoS Medicine
Public Library of Science
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Ethnic disparities in initiation and intensification of diabetes treatment in adults with type 2 diabetes in the UK, 1990–2017: A cohort study
Volume: 17, Issue: 5
DOI 10.1371/journal.pmed.1003106
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Abstract

Why was this study done?In the UK, ethnic minority populations, particularly of South Asian and black African/Caribbean descent, have a higher risk of type 2 diabetes mellitus (T2DM) and related adverse outcomes, such as cardiovascular disease, than the white population.Timely and appropriate diabetes treatment can substantially reduce risk of adverse outcomes associated with T2DM.We sought to quantify ethnic differences in time to initiation and intensification of diabetes treatment among individuals newly diagnosed with T2DM to assess whether these clinically modifiable factors may contribute to ethnic differences in outcomes.What did the researchers do and find?We used routinely recorded data from general practices across the UK to identify people newly diagnosed with T2DM and compared how long it took to initiate and intensify diabetes treatment, comparing people of white, South Asian, and black ethnicity.We found that South Asian and black groups initiated diabetes treatment more quickly than white groups but were slower to intensify to second- and third-line treatment regimes.What do these findings mean?Although time to initial treatment of type 2 diabetes was appropriate, ethnic disparities in subsequent longer-term treatment may contribute to the worse outcomes seen in ethnic minority populations in the UK.Interventions to improve timely and appropriate intensification of diabetes treatment are key to reducing disparities in the downstream adverse outcomes of T2DM.

https://www.researchpad.co/tools/openurl?pubtype=article&doi=10.1371/journal.pmed.1003106&title=Ethnic disparities in initiation and intensification of diabetes treatment in adults with type 2 diabetes in the UK, 1990–2017: A cohort study&author=Rohini Mathur,Ruth E. Farmer,Sophie V. Eastwood,Nish Chaturvedi,Ian Douglas,Liam Smeeth,Didac Mauricio,Richard Turner,Richard Turner,Richard Turner,&keyword=&subject=Research Article,Medicine and health sciences,Diagnostic medicine,Diabetes diagnosis and management,HbA1c,Biology and life sciences,Biochemistry,Proteins,Hemoglobin,HbA1c,Physical Sciences,Physics,Classical Mechanics,Motion,Inertia,Medicine and Health Sciences,Endocrinology,Endocrine Disorders,Diabetes Mellitus,Medicine and Health Sciences,Metabolic Disorders,Diabetes Mellitus,Medicine and Health Sciences,Endocrinology,Diabetic Endocrinology,Insulin,Biology and Life Sciences,Biochemistry,Hormones,Insulin,Medicine and Health Sciences,Endocrinology,Endocrine Disorders,Diabetes Mellitus,Type 2 Diabetes,Medicine and Health Sciences,Metabolic Disorders,Diabetes Mellitus,Type 2 Diabetes,Medicine and Health Sciences,Diagnostic Medicine,Diabetes Diagnosis and Management,Medicine and Health Sciences,Epidemiology,Ethnic Epidemiology,Medicine and Health Sciences,Pharmaceutics,Drug Therapy,