PLoS Neglected Tropical Diseases
Public Library of Science
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Impacts of host gender on Schistosoma mansoni risk in rural Uganda—A mixed-methods approach
Volume: 14, Issue: 5
DOI 10.1371/journal.pntd.0008266
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Abstract

Globally, over 230 million people are infected with schistosomiasis, an infectious disease caused by parasitic helminths. Humans can get infected when they contact water which contains Schistosoma parasites. Although the disease can be treated with a drug, people get rapidly reinfected in certain high-transmission settings. Drug treatment alone may not be sufficient to eliminate this disease and additional interventions such as health promotion or improvements in water and sanitation need to be scaled up. To provide recommendations to these control programmes we carried out interdisciplinary research in Eastern Uganda to understand the influence of gender on schistosomiasis risk. We found that the water contact behaviour of boys and girls is quite similar, and we did not see differences in reinfection or genetic diversity of the parasite between boys and girls. Differences in water contact between genders is greater in adults, and further research is required for these individuals. In this setting, infection rates are high in school-aged children and there are no differences between genders. These results emphasise improved control efforts for all school-aged children in communities like these. Our interdisciplinary approach provided complementary findings. Such an integrated approach can therefore have more power to meaningfully inform policy on schistosomiasis control.

https://www.researchpad.co/tools/openurl?pubtype=article&doi=10.1371/journal.pntd.0008266&title=Impacts of host gender on <i>Schistosoma mansoni</i> risk in rural Uganda—A mixed-methods approach&author=Suzan C. M. Trienekens,Christina L. Faust,Keila Meginnis,Lucy Pickering,Olivia Ericsson,Andrina Nankasi,Arinaitwe Moses,Edridah M. Tukahebwa,Poppy H. L. Lamberton,Serene A. Joseph,&keyword=&subject=Research Article,People and Places,Population Groupings,Age Groups,Children,People and Places,Population Groupings,Families,Children,Biology and Life Sciences,Genetics,Human Genetics,Medicine and Health Sciences,Parasitic Diseases,Earth Sciences,Hydrology,Surface Water,Biology and Life Sciences,Evolutionary Biology,Population Genetics,Biology and Life Sciences,Genetics,Population Genetics,Biology and Life Sciences,Population Biology,Population Genetics,Medicine and Health Sciences,Parasitic Diseases,Helminth Infections,Schistosomiasis,Medicine and Health Sciences,Tropical Diseases,Neglected Tropical Diseases,Schistosomiasis,Medicine and Health Sciences,Epidemiology,Genetic Epidemiology,Biology and Life Sciences,Psychology,Behavior,Social Sciences,Psychology,Behavior,