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Clinical trial
Interim safety analysis of the first-in-human clinical trial of the Versius surgical system, a new robot-assisted device for use in minimal access surgery
Article
Year: 2020
Pages: 10
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Therapeutic Strategies Targeting Tumor Suppressor Genes in Pancreatic Cancer
Article
Year: 2021
Pages: 1
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Evaluating the Implementation of a Multicomponent Intervention Consisting of Education and Feedback on Reducing Benzodiazepine Prescriptions by General Practitioners: BENZORED Hybrid Type I Cluster Randomized Controlled Trial
Article
Year: 2021
Pages: 1
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Randomized controlled trial of trehalose: An efficient autophagic bioprotectant in the management of dry eye disease
Article
Year: 2020
Pages: 7
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Evaluate the Therapeutic Effect of Allicin (L-cysteine) on Clinical Presentation and Prognosis in Patients with COVID-19
Article
Year: 2021
Pages: 1
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Effectiveness of Distance Technology in Promoting Physical Activity in Cardiovascular Disease Rehabilitation: Cluster Randomized Controlled Trial, A Pilot Study
Article
Year: 2021
Pages: 1
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Effect of Neprilysin Inhibition on Left Ventricular Remodeling in Patients With Asymptomatic Left Ventricular Systolic Dysfunction Late After Myocardial Infarction
Article
Year: 2021
Pages: 11
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Current evidence and challenges of systematic therapies for adult recurrent glioblastoma: Results from clinical trials
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Pages: 16
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Effectiveness of screening for tuberculosis in HIV: a pragmatic clinical trial
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Pages: 1
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Landscape and progress of global COVID-19 vaccine development
Article
Pages: 5
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Long-term follow-up of children with neuroblastoma receiving radiotherapy to metastatic lesions within the German Neuroblastoma Trials NB97 and NB 2004
Article
Year: 2020
Pages: 7
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Evaluating mechanisms of change in an oral hygiene improvement trial with older adults
Article
Year: 2021
Pages: 1
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Stem Cell Therapies for Progressive Multiple Sclerosis
Article
Year: 2021
Pages: 1
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Ozone Gel in Chronic Periodontal Disease: A Randomized Clinical Trial on the Anti-Inflammatory Effects of Ozone Application
Article
Year: 2021
Pages: 1
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A secondary analysis of a randomised controlled trial to investigate the effect of Tai Chi on the instrumented timed up and go test in people with mild to moderate dementia
Article
Year: 2020
Pages: 7
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Development of Randomized Trials in Adults with Medulloblastoma—The Example of EORTC 1634-BTG/NOA-23
Article
Year: 2021
Pages: 1
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Targeting PI3K/AKT/mTOR Signaling Pathway in Breast Cancer
Article
Year: 2021
Pages: 1
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A cost-consequence analysis of normalised advance care planning practices among people with chronic diseases in hospital and community settings
Article
Year: 2021
Pages: 1
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Quality Assessment of Studies Included in Cochrane Oral Health Systematic Reviews: A Meta-Research
Article
Year: 2021
Pages: 1
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Lysophosphatidic Acid Receptor Antagonists and Cancer: The Current Trends, Clinical Implications, and Trials
Article
Year: 2021
Pages: 1
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Curcumin: Modulator of Key Molecular Signaling Pathways in Hormone-Independent Breast Cancer
Article
Year: 2021
Pages: 1
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Nursing-Intense Health Education Intervention for Persons with Type 2 Diabetes: A Quasi-Experimental Study
Article
Year: 2021
Pages: 1
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Misreported Cancer Deaths in PLATO Trial
Article
Year: 2021
Pages: 1
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Current Concepts of Stem Cell Therapy for Chronic Spinal Cord Injury
Article
Year: 2021
Pages: 1
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Effects of a 2-Week 5000 IU versus 1000 IU Vitamin D3 Supplementation on Recovery of Symptoms in Patients with Mild to Moderate Covid-19: A Randomized Clinical Trial
Article
Year: 2021
Pages: 1
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Efficacy of an Anti-Cellulite Herbal Emgel: A Randomized Clinical Trial
Article
Year: 2021
Pages: 1
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Current Status of Baricitinib as a Repurposed Therapy for COVID-19
Article
Year: 2021
Pages: 1
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Lactobacillus plantarum
HAC01 Supplementation Improves Glycemic Control in Prediabetic Subjects: A Randomized, Double-Blind, Placebo-Controlled Trial
Article
Year: 2021
Pages: 1
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Clinical Advances of siRNA-Based Nanotherapeutics for Cancer Treatment
Article
Year: 2021
Pages: 1
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Where to Next? Research Directions after the First Hepatitis C Vaccine Efficacy Trial
Article
Year: 2021
Pages: 1
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12-month randomised trial of 360° and 180° Schlemm’s canal incisions in suture trabeculotomy ab interno for open-angle glaucoma
Article
Year: 2020
Pages: 5
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Recruitment and Retention Strategies Among Racial and Ethnic Minorities in Web-Based Intervention Trials: Retrospective Qualitative Analysis
Article
Year: 2021
Pages: 1
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Proof-of-concept study of electrospun PLGA membrane in the treatment of limbal stem cell deficiency
Article
Year: 2021
Pages: 1
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Detachable string magnetically controlled capsule endoscopy for detecting high-risk varices in compensated advanced chronic liver disease (CHESS1801): A prospective multicenter study
Article
Year: 2020
Pages: 1
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Research status on immunotherapy trials of gastric cancer
Article
Year: 2021
Pages: 12
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The effects of bright light treatment on affective symptoms in people with dementia: a 24-week cluster randomized controlled trial
Article
Year: 2021
Pages: 1
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Relacorilant, a Selective Glucocorticoid Receptor Modulator, Induces Clinical Improvements in Patients With Cushing Syndrome: Results From A Prospective, Open-Label Phase 2 Study
Article
Year: 2021
Pages: 1
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Salvage Magnetic Resonance Imaging–guided Transurethral Ultrasound Ablation for Localized Radiorecurrent Prostate Cancer: 12-Month Functional and Oncological Results
Article
Year: 2020
Pages: 9
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Effects of Wearable Transcutaneous Electrical Nerve Stimulation on Fibromyalgia: A Randomized Controlled Trial
Article
Year: 2021
Pages: 18
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The impact of non-medical cannabis legalization and other exposures on retention in longitudinal cannabis research: a survival analysis of a prospective study of Canadian medical cannabis patients
Article
Year: 2021
Pages: 1
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Preoperative walking recommendation for non-cardiac surgery patients to reduce the length of hospital stay: a randomized control trial
Article
Year: 2021
Pages: 1
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Dupilumab in Adults with Moderate-to-Severe Atopic Dermatitis and Prior Use of Systemic Non-Steroidal Immunosuppressants: Analysis of Four Phase 3 Trials
Article
Year: 2021
Pages: 16
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Automated classification of clinical trial eligibility criteria text based on ensemble learning and metric learning
Article
Year: 2021
Pages: 1
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Overcoming hurdles to intervention studies with autistic children with profound communication difficulties and their families
Article
Year: 2021
Pages: 13
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Editorial: Targets for Disease-Modifying Therapies in Alzheimer’s Disease, Including Amyloid β and Tau Protein
Article
Year: 2021
Pages: 4
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DDAH2
(-449 G/C) G allele is positively associated with leukoaraiosis in northeastern China: a double-blind, intergroup comparison, case-control study
Article
Year: 2021
Pages: 6
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Safety and efficacy of a nerve matrix membrane as a collagen nerve wrapping: a randomized, single-blind, multicenter clinical trial
Article
Year: 2021
Pages: 8
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Decision Making When Cancer Becomes Chronic: Needs Assessment for a Web-Based Medullary Thyroid Carcinoma Patient Decision Aid
Article
Year: 2021
Pages: 1
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An open-label study to evaluate biomarkers and safety in systemic sclerosis patients treated with paquinimod
Article
Year: 2021
Pages: 1
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Budesonide: A promising candidate therapeutic for early COVID-19
Article
Year: 2021
Pages: 1
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Perspective of Future SERS Clinical Application Based on Current Status of Raman Spectroscopy Clinical Trials
Article
Year: 2021
Pages: 1
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Broadly Neutralizing Antibodies for HIV-1 Prevention
Article
Year: 2021
Pages: 1
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Personalising treatment plan quality review with knowledge-based planning in the TROG 15.03 trial for stereotactic ablative body radiotherapy in primary kidney cancer
Article
Year: 2021
Pages: 1
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A Randomized Clinical Study (SEECASE) to Assess Efficacy, Safety, and Tolerability of NOV03 for Treatment of Dry Eye Disease
Article
Year: 2020
Pages: 9
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Investigator Initiated Clinical Trials (IICTs): A Systematic Search in Registries to Compare the Czech Republic and Portugal in Terms of Funding Policies and Scientific Outcomes
Article
Year: 2021
Pages: 13
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Implementing Primary Palliative Care in Post-acute nursing home care: Protocol for an embedded pilot pragmatic trial
Article
Year: 2021
Pages: 1
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Cancer stem cell-targeted chimeric antigen receptor (CAR)-T cell therapy: Challenges and prospects
Article
Year: 2020
Pages: 19
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Ropeginterferon alfa‐2b in patients with genotype 1 chronic hepatitis C: Pharmacokinetics, safety, and preliminary efficacy
Article
Year: 2021
Pages: 12
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Clinical trial enrollment at a rural satellite hospital during COVID-19 pandemic
Article
Pages: 1
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Oxidative Stress and Cognitive Alterations Induced by Cancer Chemotherapy Drugs: A Scoping Review
Article
Year: 2021
Pages: 1
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Effect of coenzyme Q10 supplementation on oxidative stress and clinical outcomes in patients with low levels of coenzyme Q10 admitted to the intensive care unit
Article
Year: 2021
Pages: 1
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Stem cell therapy for chronic obstructive pulmonary disease
Article
Year: 2021
Pages: 11
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Revealing the Threat of Emerging SARS-CoV-2 Mutations to Antibody Therapies
Article
Year: 2021
Pages: 1
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Neurofeedback Learning Is Skill Acquisition but Does Not Guarantee Treatment Benefit: Continuous-Time Analysis of Learning-Curves From a Clinical Trial for ADHD
Article
Year: 2021
Pages: 1
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Listening to Mom in the NICU: effects of increased maternal speech exposure on language outcomes and white matter development in infants born very preterm
Article
Year: 2021
Pages: 1
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Single-crown restorations supported by short implants (6 mm) compared with standard-length implants (13 mm) in conjunction with maxillary sinus floor augmentation: a randomized, controlled clinical trial
Article
Year: 2021
Pages: 1
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Moderate-intensity exercise versus high-intensity interval training to recover walking post-stroke: protocol for a randomized controlled trial
Article
Year: 2021
Pages: 1
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A prospective single-center study on CNI-free GVHD prophylaxis with everolimus plus mycophenolate mofetil in allogeneic HCT
Article
Year: 2021
Pages: 9
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Precision therapy with anaplastic lymphoma kinase inhibitor ceritinib in ALK-rearranged anaplastic large cell lymphoma
Article
Year: 2021
Pages: 1
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Incorporating radiomics into clinical trials: expert consensus endorsed by the European Society of Radiology on considerations for data-driven compared to biologically driven quantitative biomarkers
Article
Year: 2021
Pages: 12
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Low-Intensity Shockwave Therapy (LI-ESWT) in Diabetic Kidney Disease: Results from an Open-Label Interventional Clinical Trial
Article
Year: 2021
Pages: 12
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Protocol for a pharmacogenomic study on individualised antipsychotic drug treatment for patients with schizophrenia
Article
Year: 2021
Pages: 1
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A cross-sectional study in healthy elderly subjects aimed at development of an algorithm to increase identification of Alzheimer pathology for the purpose of clinical trial participation
Article
Year: 2021
Pages: 1
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A double-blind placebo-controlled randomized trial of oral saffron in the treatment of rheumatoid arthritis
Article
Pages: 11
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Receptor-Mediated Muscle Homeostasis as a Target for Sarcopenia Therapeutics
Article
Year: 2021
Pages: 13
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Analysis of the numbers of clinical trials on physical therapy in Japan: comparison with those in the North American register from 2010 to 2019
Article
Year: 2021
Pages: 5
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Short‐duration treatment with the novel non‐nucleoside inhibitor CDI‐31244 plus sofosbuvir/velpatasvir for chronic hepatitis C: An open‐label study
Article
Year: 2020
Pages: 9
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Drug repurposing in autosomal dominant polycystic kidney disease: back to the future with pioglitazone
Article
Year: 2021
Pages: 4
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Predicting Successes and Failures of Clinical Trials With Outer Product–Based Convolutional Neural Network
Article
Year: 2021
Pages: 1
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Evolving landscape and academic attitudes toward the controversies of global immuno‐oncology trials
Article
Year: 2021
Pages: 11
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Early Effects of Abaloparatide on Bone Formation and Resorption Indices in Postmenopausal Women With Osteoporosis
Article
Year: 2021
Pages: 10
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Item-Level Investigation of Participant and Study Partner Report on the Cognitive Function Index from the A4 Study Screening Data
Article
Pages: 6
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Moms in motion: weight loss intervention for postpartum mothers after gestational diabetes: a randomized controlled trial
Article
Year: 2021
Pages: 1
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Algorithm for the support of non-related (serious) adverse events in an Ebola vaccine trial in the Democratic Republic of the Congo
Article
Year: 2021
Pages: 1
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Reduced blood-stage malaria growth and immune correlates in humans following RH5 vaccination
Article
Pages: 71219
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The antiviral activity of iota-, kappa-, and lambda-carrageenan against COVID-19: A critical review
Article
Year: 2021
Pages: 1
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Clinical Equipoise in COVID‐19 Vaccine Candidates Trials
Article
Year: 2021
Pages: 1
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Regulatory concepts to guide and promote the accelerated but safe clinical development and licensure of COVID‐19 vaccines in Europe
Article
Year: 2021
Pages: 1
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Radiopharmaceutical Formulation and Preclinical Testing of
68
Ga-Labeled DOTA-MGS5 for the Regulatory Approval of a First Exploratory Clinical Trial
Article
Year: 2021
Pages: 1
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Review of PP2A Tumor Biology and Antitumor Effects of PP2A Inhibitor LB100 in the Nervous System
Article
Year: 2021
Pages: 1
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A Double-Blind Crossover RCT Analyzing Technical and Clinical Performance of Monolithic ZrO
2
Implant Fixed Dental Prostheses (iFDP) in Three Different Digital Workflows
Article
Year: 2021
Pages: 1
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Novel Therapeutic Advances in β-Thalassemia
Article
Year: 2021
Pages: 1
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Targeting CDK9 for the Treatment of Glioblastoma
Article
Year: 2021
Pages: 1
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Data Recorded in Real Life Support the Safety of Nattokinase in Patients with Vascular Diseases
Article
Year: 2021
Pages: 1
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How SARS-CoV-2 and Other Viruses Build an Invasion Route to Hijack the Host Nucleocytoplasmic Trafficking System
Article
Year: 2021
Pages: 1
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Immunogenicity and Safety of Inactivated Sabin-Strain Polio Vaccine “PoliovacSin”: Clinical Trials Phase I and II
Article
Year: 2021
Pages: 1
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Effect of Dietary Supplementation with a Natural Extract of
Sclerocarya birrea
on Glycemic Metabolism in Subjects with Prediabetes: A Randomized Double-Blind Placebo-Controlled Study
Article
Year: 2021
Pages: 1
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Adherence to oral amoxicillin dispersible tablets in children with community-acquired pneumonia enrolled in clinical trials in Malawi
Article
Year: 2021
Pages: 1
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Effects of a Single Dose of Ivermectin on Viral and Clinical Outcomes in Asymptomatic SARS-CoV-2 Infected Subjects: A Pilot Clinical Trial in Lebanon
Article
Year: 2021
Pages: 1
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RIC in COVID-19—a Clinical Trial to Investigate Whether Remote Ischemic Conditioning (RIC) Can Prevent Deterioration to Critical Care in Patients with COVID-19
Article
Year: 2021
Pages: 6
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Liposomal encapsulation of trans-crocetin enhances oxygenation in patients with COVID-19-related ARDS receiving mechanical ventilation
Article
Year: 2021
Pages: 10
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Capacity & capability building for applied dementia research in low- & middle-income countries: Two exemplars from South Asia
Article
Pages: 12
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Searching for potential surrogate endpoints of overall survival in clinical trials for patients with prostate cancer
Article
Year: 2021
Pages: 1
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Development of a core outcome set for myelodysplastic syndromes – a Delphi study from the EUMDS Registry Group
Article
Year: 2020
Pages: 13
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Hepatocellular cancer therapy in patients with HIV infection: Disparities in cancer care, trials enrolment, and cancer-related research
Article
Year: 2021
Pages: 1
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Atorvastatin induces adrenal androgen downshift in men with prostate cancer: A post Hoc analysis of a pilot adaptive Randomised clinical trial
Article
Year: 2021
Pages: 1
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Home Use of a Percutaneous Wireless Intracortical Brain-Computer Interface by Individuals With Tetraplegia
Article
Year: 2021
Pages: 13
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Post hoc analysis of ellipsoid zone changes beyond the central subfield in symptomatic vitreomacular adhesion patients from the OASIS trial
Article
Year: 2021
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Comparison of regulatory framework of clinical trial with genetically modified organism-containing vaccines in the Europe, Australia, and Switzerland
Article
Year: 2021
Pages: 13
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An international, randomized, placebo‐controlled, phase 2b clinical trial of intepirdine for dementia with Lewy bodies (HEADWAY‐DLB)
Article
Year: 2021
Pages: 1
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Clinical usefulness of eribulin as first- or second-line chemotherapy for recurrent HER2-negative breast cancer: a randomized phase II study (JBCRG-19)
Article
Year: 2021
Pages: 8
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Potential Virus Involvement in Alzheimer’s Disease: Results from a Phase IIa Trial Evaluating Apovir, an Antiviral Drug Combination
Article
Pages: 19
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β-Lactolin Enhances Neural Activity, Indicated by Event-Related P300 Amplitude, in Healthy Adults: A Randomized Controlled Trial
Article
Pages: 10
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Association of Plasma Hemoglobin A1c with Improvement of Cognitive Functions by Probiotic
Bifidobacterium breve
Supplementation in Healthy Adults with Mild Cognitive Impairment
Article
Pages: 5
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A Precision Medicine Approach to Treating Alzheimer’s Disease Using Rosiglitazone Therapy: A Biomarker Analysis of the REFLECT Trials
Article
Pages: 12
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The immunogenicity and safety of respiratory syncytial virus vaccines in development: A systematic review
Article
Year: 2021
Pages: 13
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Changes in Drug Utilization After Publication of Clinical Trials and Drug-Related Scandals in Japan: An Interrupted Time Series Analysis, 2005–2017
Article
Year: 2021
Pages: 7
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Comparison of the injection‐site experience of the starting doses with semaglutide and dulaglutide: A randomized, double‐blind trial in healthy subjects
Article
Year: 2021
Pages: 5
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Survival assessment of the extended‐wear insulin infusion set featuring lantern technology in adults with type 1 diabetes by the glucose clamp technique
Article
Year: 2021
Pages: 7
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Hand Osteoarthritis: investigating Pain Effects of estrogen-containing therapy (HOPE-e): a protocol for a feasibility randomised placebo-controlled trial
Article
Year: 2021
Pages: 1
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Results of a randomized phase III/IV trial comparing intermittent bolus versus continuous infusion of antihaemophilic factor (recombinant) in adults with severe or moderately severe haemophilia A undergoing major orthopaedic surgery
Article
Year: 2021
Pages: 9
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Baseline characteristics and comparability of older multimorbid patients with polypharmacy and general practitioners participating in a randomized controlled primary care trial
Article
Year: 2021
Pages: 1
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Potential Disease-Modifying Effects of Lithium Carbonate in Niemann-Pick Disease, Type C1
Article
Year: 2021
Pages: 1
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A Minireview of the Promising Drugs and Vaccines in Pipeline for the Treatment of COVID-19 and Current Update on Clinical Trials
Article
Year: 2021
Pages: 1
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Efficacy of a Low Dose of Melatonin as an Adjunctive Therapy in Hospitalized Patients with COVID-19: A Randomized, Double-blind Clinical Trial
Article
Year: 2021
Pages: 7
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Effect of Antimicrobial Contact Lenses on Corneal Infiltrative Events: A Randomized Clinical Trial
Article
Year: 2021
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Characterisation of mesenchymal stromal cells in clinical trial reports: analysis of published descriptors
Article
Year: 2021
Pages: 1
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US Food and Drug Administration regulatory updates in neuro-oncology
Article
Year: 2021
Pages: 7
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Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies
Article
Year: 2021
Pages: 1
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The 5P program, personalized and participatory primary prevention pathway: Rational and design of a clinical trial in general practice
Article
Year: 2021
Pages: 1
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Long-Term Efficacy and Safety of Ozanimod in Moderately to Severely Active Ulcerative Colitis: Results From the Open-Label Extension of the Randomized, Phase 2 TOUCHSTONE Study
Article
Year: 2021
Pages: 10
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Frequency of repositioning for preventing pressure ulcers in patients hospitalized in ICU: protocol of a cluster randomized controlled trial
Article
Year: 2021
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TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis
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Year: 2021
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WOMAN-PharmacoTXA trial: Study protocol for a randomised controlled trial to assess the pharmacokinetics and pharmacodynamics of intramuscular, intravenous and oral administration of tranexamic acid in women giving birth by caesarean section
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Lewy Body Dementia Association’s Industry Advisory Council: proceedings of the second annual meeting
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Acenocoumarol Pharmacogenetic Dosing Algorithm versus Usual Care in Patients with Venous Thromboembolism: A Randomised Clinical Trial
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Complement System and Potential Therapeutics in Age-Related Macular Degeneration
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Year: 2021
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The appearance and increase in the quantity and proportion of the clinical research coordinator’s service fee in drug clinical trial research fund and its impact on trial quality
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Beta-hydroxy beta-methylbutyrate/arginine/glutamine (HMB/Arg/Gln) supplementation to improve the management of cachexia in patients with advanced lung cancer: an open-label, multicentre, randomised, controlled phase II trial (NOURISH)
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Safety and efficacy of rabies immunoglobulin in pediatric patients with suspected exposure
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Challenges and opportunities in setting up a phase III vaccine clinical trial in resource limited settings: Experience from Nepal
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A randomized phase 1 study of the safety and immunogenicity of 2 novel pneumococcal conjugate vaccines in healthy Japanese adults in the United States
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Response of the trial innovation network to the COVID-19 pandemic
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Essential oils for agitation in dementia [rELOAD]: A pragmatic, cluster-randomized, placebo-controlled, pilot feasibility trial
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CAR T Cell-Based Immunotherapy for the Treatment of Glioblastoma
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Year: 2021
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Assessment of the Clinical Trials Safety Profile of PD-1/PD-L1 Inhibitors Among Patients With Cancer: An Updated Systematic Review and Meta-Analysis
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Bendamustine treatment of Chinese patients with relapsed indolent non-Hodgkin lymphoma: a multicenter, open-label, single-arm, phase 3 study
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Year: 2021
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Transdermal nicotine in non-smokers: A systematic review to design COVID-19 clinical trials
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Year: 2021
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A phase I study of the safety and activity of K-001 in patients with advanced pancreatic ductal adenocarcinoma
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Year: 2021
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Social media attention and citations of published outputs from re-use of clinical trial data: a matched comparison with articles published in the same journals
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A framework for handling missing accelerometer outcome data in trials
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Year: 2021
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Effects of bilateral subthalamic nucleus deep brain stimulation on motor symptoms in Parkinson’s disease: a retrospective cohort study
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Machine Learning-Based Prediction of Brain Tissue Infarction in Patients With Acute Ischemic Stroke Treated With Theophylline as an Add-On to Thrombolytic Therapy: A Randomized Clinical Trial Subgroup Analysis
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Dual inhibition of complement component 5 and leukotriene B4 by topical rVA576 in atopic keratoconjunctivis: TRACKER phase 1 clinical trial results
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Year: 2021
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Clinical and Basic Research Progress on Treg-Induced Immune Tolerance in Liver Transplantation
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Current Understanding of Neurofibromatosis Type 1, 2, and Schwannomatosis
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Year: 2021
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Digital Technology in Clinical Trials for Multiple Sclerosis: Systematic Review
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A phase 1/2 open label nonrandomized clinical trial of intravenous 2-hydroxypropyl-β-cyclodextrin for acute liver disease in infants with Niemann-Pick C1
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Translating the Investigator’s Static Global Assessment to the Eczema Area and Severity Index in Studies of Crisaborole for Atopic Dermatitis
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Year: 2021
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The Effects of Martial Arts on Cancer-Related Fatigue and Quality of Life in Cancer Patients: An Up-to-Date Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
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Year: 2021
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Evaluating the clinical utility of early exome sequencing in diverse pediatric outpatient populations in the North Carolina Clinical Genomic Evaluation of Next-generation Exome Sequencing (NCGENES) 2 study: a randomized controlled trial
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Year: 2021
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Long-Term Clinical and Immunological Effects of Repeated Mesenchymal Stem Cell Injections in Patients With Progressive Forms of Multiple Sclerosis
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Year: 2021
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The Immunology of Hormone Receptor Positive Breast Cancer
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Year: 2021
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The cerebral mechanism underlying the acupoints with specific effect for gallbladder stone disease: protocol for a randomized controlled task-fMRI trial
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Effects of seated lumbar rotation manipulation in treating degenerative lumbar instability: a protocol for a randomized controlled trial
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Year: 2021
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Age specific recruitment and retention to a large multicentre observational breast cancer trial in older women: The Age Gap Trial
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Efficacy of an infant formula manufactured from a specific protein hydrolysate derived from whey protein isolate and concentrate produced by Société des Produits Nestlé S.A. in reducing the risk of developing atopic dermatitis
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Year: 2021
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Childbearing vs. clinical trial participation: is it one or the other?
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Year: 2021
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Microbiome recovery in adult females with uncomplicated urinary tract infections in a randomised phase 2A trial of the novel antibiotic gepotidacin (GSK140944)
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Challenges of Recruiting Patients Into Group-Based Stroke Rehabilitation Research: Reflections on Clinician Equipoise Within the Singing for People With Aphasia (SPA) Pilot Trial
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Accelerator-based BNCT for patients with recurrent glioblastoma: a multicenter phase II study
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Year: 2021
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Effects of an Avocado-based Mediterranean Diet on Serum Lipids for Secondary Prevention after Ischemic Stroke Trial (ADD-SPISE)
Study protocol
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Year: 2021
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An update on targeted therapies in systemic sclerosis based on a systematic review from the last 3 years
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Year: 2021
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Tumor-Treating Fields Therapy for Pediatric Brain Tumors
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Year: 2021
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Clinical Application of Cytokines in Cancer Immunotherapy
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The role of tazemetostat in relapsed/refractory follicular lymphoma
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Year: 2021
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Intepirdine as adjunctive therapy to donepezil for mild‐to‐moderate Alzheimer's disease: A randomized, placebo‐controlled, phase 3 clinical trial (MINDSET)
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Year: 2021
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Clinical trial of autologous adipose tissue-derived regenerative (stem) cells therapy for exploration of its safety and efficacy
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Year: 2021
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Deep exploration of PARP inhibitors in breast cancer: monotherapy and combination therapy
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Year: 2021
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Traditional Chinese medicine shenhuang granule in patients with severe/critical COVID-19: A randomized controlled multicenter trial
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A Systematic Review and Meta-Analyses of Interventional Clinical Trial Studies for Gene Therapies for the Inherited Retinal Degenerations (IRDs)
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A phase 2 double-blind placebo-controlled 24-week treatment clinical study of the p38 alpha kinase inhibitor neflamapimod in mild Alzheimer’s disease
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Novel Target Opportunities in Non-Metastatic Castrate Resistant Prostate Cancer
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Stay on Target: Reengaging Cancer Vaccines in Combination Immunotherapy
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Is It Time for Quotas to Achieve Racial and Ethnic Representation in Multiple Sclerosis Trials?
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Year: 2021
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Effect of Polydextrose/Fructooligosaccharide Mixture on Constipation Symptoms in Children Aged 4 to 8 Years
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CD137 as an Attractive T Cell Co-Stimulatory Target in the TNFRSF for Immuno-Oncology Drug Development
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Modifying gut integrity and microbiome in children with severe acute malnutrition using legume-based feeds (MIMBLE): A pilot trial
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Year: 2021
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Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder
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Year: 2021
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The Assisted Breathing before Cord Clamping (ABC) Study Protocol
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Year: 2021
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Parental and professional perceptions of informed consent and participation in a time-critical neonatal trial: a mixed-methods study in India, Sri Lanka and Bangladesh
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Year: 2021
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The Herbal Formula CWBSD Improves Sleep Quality Dependent on Oral Microbial Type and Tongue Diagnostic Features in Insomnia
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Year: 2021
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Experimental design of the Effects of Dehydroepiandrosterone in Pulmonary Hypertension (EDIPHY) trial
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Year: 2021
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Anastrozole and levonorgrestrel-releasing intrauterine device in the treatment of endometriosis: a randomized clinical trial
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An investigation of the effectiveness of oral cyclosporine on perioperative myocardial injury (PMI) in patients who undergo the surgical procedure of coronary artery bypass graft (CABG): A Randomized Controlled Clinical Trial
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Year: 2021
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Influence of equipment changes on MRI measures of brain atrophy and brain microstructure in a placebo-controlled trial of ibudilast in progressive multiple sclerosis
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Year: 2021
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A phase II study of gemcitabine plus nab-paclitaxel as first-line therapy for locally advanced pancreatic cancer
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Year: 2021
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The statistical approach in trial-based economic evaluations matters: get your statistics together!
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Year: 2021
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COVID-19 trial graph: a linked graph for COVID-19 clinical trials
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Year: 2021
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Extended single-dose toxicity study of [
211
At]NaAt in mice for the first-in-human clinical trial of targeted alpha therapy for differentiated thyroid cancer
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Year: 2021
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Implementation of Wearable Sensors and Digital Alerting Systems in Secondary Care: Protocol for a Real-World Prospective Study Evaluating Clinical Outcomes
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Mitochondrial and metabolic dysfunction in Friedreich ataxia: update on pathophysiological relevance and clinical interventions
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A review on the neuroprotective effects of hyperbaric oxygen therapy
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Year: 2021
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Treatment of Executive Function Deficits in autism spectrum disorder with repetitive transcranial magnetic stimulation: A double-blind, sham-controlled, pilot trial
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Year: 2020
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Customized Root-Analogue Implants: A Review on Outcomes from Clinical Trials and Case Reports
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Year: 2021
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Efficacy and Safety of Sea Salt-Derived Physiological Saline Nasal Spray as Add-On Therapy in Patients with Acute Upper Respiratory Infection: A Multicenter Retrospective Cohort Study
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Year: 2021
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fMRI as an outcome measure in clinical trials: A systematic review in clinicaltrials.gov
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Year: 2021
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The immune microenvironment and relation to outcome in patients with advanced breast cancer treated with docetaxel with or without gemcitabine
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Technology clinical trials: Turning innovation into patient benefit
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Year: 2021
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Confronting Covid-19 by exploring the possibility of vaccinating with live SARS-CoV-2 virus itself, via a route that would reduce the incidence of pulmonary complications
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Year: 2020
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The Updated Role of the Blood Brain Barrier in Subarachnoid Hemorrhage: From Basic and Clinical Studies
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Efficacy of
Bifidobacterium bifidum
G9-1 in improving quality of life in patients with chronic constipation: a prospective intervention study
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Year: 2021
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Randomized, phase 1/2, double-blind pioglitazone repositioning trial combined with antifungals for the treatment of cryptococcal meningitis – PIO study
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Year: 2021
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Breast Cancer Therapeutics and Biomarkers: Past, Present, and Future Approaches
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Year: 2021
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Ibudilast (MN-166) in amyotrophic lateral sclerosis- an open label, safety and pharmacodynamic trial
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Year: 2021
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The Impact of COVID-19 on National Clinical Trials Network Breast Cancer Trials
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Year: 2021
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REL-1017 (Esmethadone) Increases Circulating BDNF Levels in Healthy Subjects of a Phase 1 Clinical Study
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Year: 2021
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Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed People with HIV Aged ≥ 65 Years: Week 48 Results of a Phase 3b, Open-Label Trial
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Year: 2021
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Global Trend in Research and Development of CDK4/6 Inhibitors for Clinical Cancer Therapy: A Bibliometric Analysis
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Year: 2021
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Allogeneic stem cell transplantation for mantle cell lymphoma—update of the prospective trials of the East German Study Group Hematology/Oncology (OSHO#60 and #74)
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Year: 2021
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Glibenclamide Advantage in Treating Edema After Intracerebral Hemorrhage (GATE-ICH): Study Protocol for a Multicenter Randomized, Controlled, Assessor-Blinded Trial
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Year: 2021
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Effect of acupuncture treatment in patients with mild to moderate atopic dermatitis: a randomized, participant- and assessor-blind sham-controlled trial
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Year: 2021
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Travel barriers, unemployment, and external fixation predict loss to follow-up after surgical management of lower extremity fractures in Dar es Salaam, Tanzania
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Stakeholder involvement in the development of trial material for a clinical trial
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Year: 2020
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Recommendations for cellular and molecular pathology input into clinical trials: a systematic review and meta‐aggregation
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Year: 2021
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Effects of Shuanghuanglian oral liquids on patients with COVID-19: a randomized, open-label, parallel-controlled, multicenter clinical trial
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Year: 2021
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Building an OMOP common data model-compliant annotated corpus for COVID-19 clinical trials
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Year: 2021
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Effect of a Multifactorial Intervention on Fracture in Patients With Type 2 Diabetes: Subanalysis of the J-DOIT3 Study
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Year: 2021
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Adaptive Homeostatic Strategies of Resilient Intrinsic Self-Regulation in Extremes (RISE): A Randomized Controlled Trial of a Novel Behavioral Treatment for Chronic Pain
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Trends of Stem Cell Therapies in Age-Related Macular Degeneration
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Year: 2021
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Andrographis paniculata
(Burm. f.) Wall. ex Nees: An Updated Review of Phytochemistry, Antimicrobial Pharmacology, and Clinical Safety and Efficacy
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Year: 2021
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Neuroimaging mechanisms of high-frequency repetitive transcranial magnetic stimulation for treatment of amnestic mild cognitive impairment: a double-blind randomized sham-controlled trial
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Year: 2020
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Association between plasma immunoproteasome and 90-day prognosis after first-ever ischemic stroke
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Year: 2020
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Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial
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Year: 2021
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Stakeholder-engaged process for refining the design of a clinical trial in home hospice
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Year: 2021
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Experiences with simultaneous use of contraception and the vaginal ring for HIV prevention in sub-Saharan Africa
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Year: 2021
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Sociodemographic, Behavioral and Oral Health Factors in Maternal and Child Health: An Interventional and Associative Study from the Network Perspective
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Year: 2021
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Virtual Environment Rehabilitation for Patients with Motor Neglect Trial (VERMONT): A Single-Center Randomized Controlled Feasibility Trial
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Year: 2021
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The IHAT-GUT Iron Supplementation Trial in Rural Gambia: Barriers, Facilitators, and Benefits
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Year: 2021
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Development of a Digital Research Assistant for the Management of Patients’ Enrollment in Oncology Clinical Trials within a Research Hospital
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Year: 2021
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What Is the State-of-the-Art in Clinical Trials on Vaccine Hesitancy 2015–2020?
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Year: 2021
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Tetrodotoxin for Chemotherapy-Induced Neuropathic Pain: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Dose Finding Trial
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Year: 2021
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Effects of Ivermectin in Patients With COVID-19: A Multicenter, Double-blind, Randomized, Controlled Clinical Trial
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Year: 2021
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Daptomycin Plus Fosfomycin Versus Daptomycin Alone for Methicillin-resistant
Staphylococcus aureus
Bacteremia and Endocarditis: A Randomized Clinical Trial
Article
Year: 2020
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Ceftolozane-tazobactam versus meropenem for definitive treatment of bloodstream infection due to extended-spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacterales (“MERINO-3”): study protocol for a multicentre, open-label randomised non-inferiority trial
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Year: 2021
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Impact of COVID-19 pandemic on the oncologic care continuum: urgent need to restore patients care to pre-COVID-19 era
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Computerized-Adaptive vs. Traditional Ratings of Depression and Suicidal Thoughts: An Assay Sensitivity Pilot Study in a Ketamine Clinical Trial
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Year: 2021
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Using historical data to facilitate clinical prevention trials in Alzheimer disease? An analysis of longitudinal MCI (mild cognitive impairment) data sets
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Year: 2021
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Checkpoint inhibition in combination with an immunoboost of external beam radiotherapy in solid tumors (CHEERS): study protocol for a phase 2, open-label, randomized controlled trial
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Year: 2021
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The Application of Zonisamide to Patients Suffering from Dementia with Lewy Bodies: Emerging Clinical Data
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Year: 2021
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Making the patient voice heard in a research consortium: experiences from an EU project (IMI-APPROACH)
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Year: 2021
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A novel dominant-negative PD-1 armored anti-CD19 CAR T cell is safe and effective against refractory/relapsed B cell lymphoma
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Year: 2021
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Data Sharing Goals for Nonprofit Funders of Clinical Trials
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Year: 2021
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Transitioning to Remote Clinic Visits in a Smoking Cessation Trial During the COVID-19 Pandemic: Mixed Methods Evaluation
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Year: 2021
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Uncovering the Bone-Muscle Interaction and Its Implications for the Health and Function of Older Adults (the Wellderly Project): Protocol for a Randomized Controlled Crossover Trial
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Year: 2021
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Randomised controlled trial of oxygen therapy and high-flow nasal therapy in African children with pneumonia
Article
Year: 2021
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Beneficial Potential of
Banha-Sasim-Tang
for Stress-Sensitive Functional Dyspepsia via Modulation of Ghrelin: A Randomized Controlled Trial
Article
Year: 2021
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The safety, tolerability and pharmacokinetics of niraparib in Japanese patients with solid tumours: results of a phase I dose-escalation study
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Year: 2021
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Response-shift effects in neuromyelitis optica spectrum disorder: a secondary analysis of clinical trial data
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Year: 2020
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Pharmaceutical Aspects and Clinical Evaluation of COVID-19 Vaccines
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Per-Treatment
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A Clinical Trial to Evaluate the Efficacy of α-Viniferin in
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The Effect of Foot Reflexology on Amnesia in Patients Undergoing Electroconvulsive Therapy: A Randomized Clinical Trial
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Improved gastrointestinal profile with diroximel fumarate is associated with a positive impact on quality of life compared with dimethyl fumarate: results from the randomized, double-blind, phase III EVOLVE-MS-2 study
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Rationale and Design of BeatNF2 Trial: A Clinical Trial to Assess the Efficacy and Safety of Bevacizumab in Patients with Neurofibromatosis Type 2 Related Vestibular Schwannoma
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Heterogeneity of national legislation and practice on clinical trials with vulnerable patients based on the EU Clinical Trials Directive by the example of adults permanently incapable of giving informed consent
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Overcoming the impact of the COVID‐19 pandemic on oncology early phase trials and drug development in Asia—Experiences and perspectives of the Asian Oncology Early Phase 1 Consortium
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Proceedings From the First International Workshop at Sidra Medicine: “Engineered Immune Cells in Cancer Immunotherapy (EICCI): From Discovery to Off-the-Shelf Development”, 15
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