ResearchPad - enantioselective-synthesis-|-hot-paper Default RSS Feed en-us © 2020 Newgen KnowledgeWorks <![CDATA[Iridium‐Catalyzed Enantioselective Intermolecular Indole C2‐Allylation]]> An enantioselective C2‐allylation of 3‐substituted indoles is reported, providing C2‐allylated products with excellent regiocontrol. Experimental studies and DFT calculations suggest that the reaction proceeds via direct C2‐allylation with steric congestion at the indole‐C3 position and π–π stacking interactions identified as major contributors to the selectivity observed.