ResearchPad - news-and-commentary Default RSS Feed en-us © 2020 Newgen KnowledgeWorks <![CDATA[AMPK, a key regulator of metabolic/energy homeostasis and mitochondrial biogenesis in cancer cells]]> <![CDATA[Cracking the code of neuronal apoptosis and survival]]> Neuronal apoptosis and survival are tightly controlled processes that regulate cell fate during the development of the central nervous system and its homeostasis throughout adulthood. A new study in primary cultures of cerebellar granule neurons identified common transcriptional cascades during rescue from apoptosis by insulin-like growth factor-1 (Igf1) and pituitary adenylyl cyclase-activating polypeptide (Pacap), thus suggesting the existence of a high degree of conservation of cell survival pathways.

<![CDATA[Bivalent IAP antagonists inhibit TRAF2-bound cIAPs and limit TNF-mediated NF-<i>κ</i>B signaling]]>