ResearchPad - news-and-commentary https://www.researchpad.co Default RSS Feed en-us © 2020 Newgen KnowledgeWorks <![CDATA[AMPK, a key regulator of metabolic/energy homeostasis and mitochondrial biogenesis in cancer cells]]> https://www.researchpad.co/article/Naa6b81aa-6a87-4294-9f96-3926bb4be8b1 <![CDATA[Cracking the code of neuronal apoptosis and survival]]> https://www.researchpad.co/article/Na3e54cfa-958b-4c96-af12-fb04998dc2f7 Neuronal apoptosis and survival are tightly controlled processes that regulate cell fate during the development of the central nervous system and its homeostasis throughout adulthood. A new study in primary cultures of cerebellar granule neurons identified common transcriptional cascades during rescue from apoptosis by insulin-like growth factor-1 (Igf1) and pituitary adenylyl cyclase-activating polypeptide (Pacap), thus suggesting the existence of a high degree of conservation of cell survival pathways.

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<![CDATA[Bivalent IAP antagonists inhibit TRAF2-bound cIAPs and limit TNF-mediated NF-<i>κ</i>B signaling]]> https://www.researchpad.co/article/Nbbf5d38a-a9e8-42f7-91c0-8c686a8b1da9